MaquiRx – 30 Capsules

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MaquiRx – 30 Capsules
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Rated 4.56 out of 5 based on 50 customer ratings
(50 customer reviews)

Maqui berry has been shown to help activate AMP-Kinase, a gene that plays a key role in energy balance and metabolism. Activation of AMP-Kinase has been shown to help with appetite control, blood sugar support, lipid levels, reduction of inflammation and repair of damaged tissue. This is why Dr. Sears calls maqui the best of the best when it comes to polyphenols.

Benefits of MaquiRx:
  • Maqui Berry is one of the richest antioxidant sources known, having three times more antioxidants than blackberries, blueberries, strawberries, and raspberries.
  • Maqui berries have the highest concentration of a subclass of polyphenols called delphinidins, which can enter the blood more easily than other polyphenols, thus supporting activation of AMP kinase.
  • Maqui berry extract has been clinically shown to support improved blood sugar levels and reduced oxidative stress.
  • Source of anti-oxidants to help minimize free radical formation and anti-aging.
  • Supplies 120 mg of polyphenols per serving.
  • Helps support a healthy gut.
  • Free of sugar commonly found in fruits.
  • Third party tested for purity.
  • Easy to swallow vegetarian capsule.

Suggested Use: Take one (1) capsule daily with a meal for optimal absorption. 30 servings per bottle.

What are Polyphenols? 

Polyphenols are nutrients found in plants that are responsible for their health-promoting properties. The more colorful the plant, generally the higher the polyphenol content. This is why fruits, especially berries, and vegetables are good sources of polyphenols.

Polyphenols offer plants protection against the sun’s radiation and help defend against disease. They protect us in a similar way by acting as antioxidants to help combat inflammation and aid in improving immunity through their activation of key genes. The antioxidant capacity of polyphenols is 3x greater than those found in traditional antioxidants like vitamins A, C and E.


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  • Science
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  • Reviews (50)
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  • Purity Data

Polyphenols Are…

Polyphenols give fruits and vegetables their bright colors. Until recently, little was known about polyphenols. We now know they are powerful activators of genes. In particular, polyphenols can activate the genes necessary for the production of anti-oxidant, anti-inflammatory, and anti-aging enzymes.

You Need Polyphenols Because…

Polyphenols maintain a healthy gut by promoting an optimal microbial composition. Although polyphenols are not yet considered essential nutrients, you have to have adequate levels in the diet on a daily basis to continually activate the genes required for optimal health, especially for gut health.

Polyphenols Help You Eat Less by…

Polyphenols help support the enzymes that optimize metabolism so that you can promote higher energy levels.

Supplementing with Polyphenols is Important Because…

Polyphenol supplements can be concentrated to higher levels making it more likely for the body to get adequate levels on a daily basis to maintain optimal wellness.

MaquiRx - 30 Capsules - Supplement Facts

50 reviews for MaquiRx – 30 Capsules

  1. Rated 4 out of 5

    Alberto Fernandez

    Been on the Zone since the 90’s when Dr. Sears was not selling any products to be in the Zone. I am living proof and a believer of Dr. Sears. I am slim, healthy (zero meds) and strong.
    Now I try to take it one step higher with Polyphenols but the MaquiRX label suggests one capsule per day and in other literature Dr. Sears mentions 4 capsules per day. That is a big difference and cost.
    Please explain.

    • Dr. Sears’ Zone

      Alberto, Thank you for your comment/question and for being a long time Zoner. With the MaquiRx, 1 capsule contains 300mg of the maqui berry extract Delphinol and provides 120mg of total polyphenols. Dr. Sears does suggest that a person should get at least 1000mg of polyphenols per day with much of your daily intake coming from dietary sources of fruits and vegetables. If a person is looking to get a higher percentage of their polyphenols in the form of delphinidins from the maqui berry or if they are not eating their daily supply of fruits and vegetables it can be beneficial to take additional MaquiRx capsules. Thank You, Dr. Sears’ Zone

  2. Rated 1 out of 5

    Brocker Krocker

    After taking these I feel absolutely no improvement in my health. This is basically blueberry flavoured chalk.

  3. Rated 5 out of 5

    John Edwards (verified owner)

    Ordering was a breeze, delivered earlier than expected and the bottle was as sealed/secured – definitely will order again

  4. Rated 5 out of 5

    Joonhong Jang

    I believe it makes me feel better.

  5. Rated 5 out of 5

    Ruth Hernández

    Hello I’m a Doctor OBGYN and I prescribe Zone maqui, my patients came with another brand, and my question is would it work the same way? The brand is BIOVEA maqui berry 500mg.

    • Dr. Sears’ Zone Customer Support

      Thank you for your question Dr. Hernandez. We have reviewed the Biovea product and while it does contain maqui berry there is one aspect of the product that is quite different than the MaquiRx. According to the label, the Biovea product contains 500mg of “whole fruit” from the maqui berry while Dr. Sears’ MaquiRx is a maqui berry extract containing 300mg of the highly purified delphinidin extract. Delphinidins are a special class of polyphenols that have unique anti-oxidant, anti-inflammatory, and anti-aging properties that work by activating the key enzyme AMP kinase that controls our metabolism, increases chemical energy production, and provides anti-aging benefits. As far as how much of the delphinidins are in the Biovea product, that would be difficult to say since they do not share that information in the product information or supplement facts. Thank You, Dr. Sears’ Zone

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What are Polyphenols?

Polyphenols are the chemicals that give vegetables and fruits their colors. They also represent the plant’s primary defense mechanism against invading bacteria and other parasites. Their intake is important in controlling the bacteria composition of our digestive system.

What do Polyphenols do for you?

It is becoming recognized that polyphenols are essential nutrients for humans. They are powerful anti-oxidants, have anti-inflammatory effects, and activate the key enzyme (AMP kinase) that controls our metabolism, increases chemical energy production, and slows down the aging process. Equally important, you need adequate levels of polyphenols to maintain the appropriate balance of bacteria in your gut that is key to maintaining long-term health. If that balance is disturbed by a lack of polyphenols in your diet, the result will be increased cellular inflammation throughout your body.

How many Polyphenols do you need?

From an anti-oxidant potential you need to ingest enough fruits and vegetables to provide a minimum of 3,000-5,000 Oxygen Radical Absorption Capacity (ORAC) units per day. Unfortunately, to reach the minimum 3,000-5,000 ORAC units requires approximately 10 servings of normally consumed fruits and vegetables per day. Dr. Sears recommends at least 10,000 ORAC units per day for optimal anti-oxidant and anti-inflammatory benefits. To reach the recommended levels of 10,000 ORAC units per day, it does require additional polyphenol supplementation for most people. The good news it that one capsule of any of our polyphenol products will provide an additional 8,000 ORAC units.

Are all Polyphenols the same?

No. There are about 4,000 known polyphenols. All have some anti-oxidative properties, but relatively few are anti-inflammatory, and even fewer have anti-aging benefits. Furthermore, you need highly purified polyphenol extracts like those used in Zone Polyphenols to get the full potential of their anti-inflammatory and anti-aging properties.

Why are Zone Polyphenols different than others on the market?

To get the full potential of the anti-inflammatory and anti-aging properties of polyphenols, you have to use highly purified extracts. They are more expensive than typical concentrates because of the extra processing, but without such purification you are unlikely see any of their potential benefits.

Why are Delphinidins "the Best of the Best"?

Delphinidins are the only polyphenols that are common to red wine, dark chocolate, and blueberries. Delphinidins have a unique structure compared to all other polyphenols that allows them to provide unique anti-inflammatory and anti-aging benefits. The richest source of delphinidins is the maqui berry found only in the Patagonian region of Chile. One capsule of Maqui Rx contains the highly purified polyphenol extract of the maqui berry and has the same amount of delphinidins as found in 100 bottles of red wine, 20 bars of dark chocolate, or 5 pounds of blueberries.

Purity Counts when choosing Polyphenols

We test every lot of finished product and have begun posting the report results because our consumers deserve to know what they’re taking. To have Dr. Sears’ name on every bottle, it has to meet his strict standards for concentration and purity and stability, plus be certified for sports usage. See how our MaquiRx measures up.

Independent Third-Party Testing Reports