This is because neuroinflammation persists long after the concussion. The best marker that the neuroinflammation from a concussion has resolved is the AA/EPA ratio. The good range is between 1.5 and 3.
Wrong use of terms in this article. They should be talking about ketogenic diets, not higher-protein diets rich in fruits and vegetables (i.e., the Zone Diet). Likewise, the last place I would go to get information on healthy diets is the USDA.
You can only make Resolvin D1 (RvD1) if you have high levels of DHA in the blood. When the AA/EPA ratio is under 2, then you see an increase in RvD1 production.
Part of those genetics appears to be a more rapid oxidation of omega-3 fatty acids (Ross et al. Nutr Neurosci 2003, 6(5) p277-81)
NAPE is N-oleoylphosphatidylethanolamine. It is derived from oleic acid that comes from olive oil, guacamole, and nuts. The more oleic acid you consume, the more NAPE you make.
To solve this dilemma, you need new markers of wellness that are independent of body fat. My newest book, The Mediterranean Zone, discusses those markers.
I think I have been saying this more than 13 years ago when I published The OmegaRx Zone that described the potential of high-dose omega-3 fatty acids to treat depression. The reason that EPA works better than DHA is EPA is rapidly transformed into resolvins in the brain that put out inflammatory fires as I described in my newest book, The Mediterranean Zone.
If you have an “obesity gene,” it means you should spend more time trying to induce satiety by following an anti-inflammatory diet instead of exercising more, which makes you even hungrier.
Flavorings have been used for hundreds of years to enhance the taste of any food. The reason we have an obesity epidemic is inflammation is making us hungrier than in the past.
I discussed this in my book Toxic Fat, published in 2008. Many diabetic patients have healthy fat cells that can prevent the massive lipotoxicity that causes the early mortality in diabetics. This is also seen in animal studies in which obese diabetic animals can be made into super-obese animals with a dramatic reduction of their symptoms of diabetes.