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Zone Cognitive Support is formulated with S-adenosyl-L-methionine (SAMe), a natural supplement that provides the necessary methyl groups required to turn on and off DNA replication, especially in neural regeneration as well as in transmission of neural impulses. SAMe is also known to be essential to at least 35 other biochemical processes including maintaining a healthy mood.1 The brain of a healthy person manufactures all the SAM it needs, but SAM production is impaired in those that have mood related problems.2 Supplementation with SAMe boosts levels of serotonin and other neurotransmitters such as dopamine.3,4,5 This form of methionine is more likely to cross the blood-brain barrier where it affects the synthesis and activation of various neurotransmitters in the brain.6,7*
- Supports Serotonin Production
- Boosts mood
- B vitamins added
- Double enteric coating
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. |
Supplement Facts
References
Supplement Facts
Serving Size: One Capsule
Servings Per Container: 60 |
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Amount
Per Serving |
% Daily
Value* |
|
|
Vitamin B-6 (as Pyridoxine HCl) |
2 |
mg |
100% |
|
Folic Acid |
200 |
mcg |
50% |
|
Vitamin B-12 (as Cyanocabalamin) |
50 |
mcg |
833% |
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|
SAMe (S-Adenosyl-L-Methionine) |
200 |
mg |
** |
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|
* Percent Daily Values are based on a 2000 calorie diet.
** Daily Value Not Established |
Other Ingredients: Cellulose, Croscarmellose Sodium, Methacrylic Acid, Magnesium Stearate, Silica, Triethyl Citrate, Stearic Acid, Citric Acid and Ascorbic Acid. |
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| Free of: yeast, corn, soy, wheat, milk or gluten | |
1 Bell, KM, et al, “S-Adenosylmethionine blood levels in major depression: changes with drug treatment.” Acta Neurologica Scandinavica; 1994; 154:15-18.
2 Murray, MT, Natural Alternatives to Prozac, Quill, New York, NY, 1996; p. 174-175.
3 Young, S, “The Use of Diet and Dietary Components in the Study of Factors Controlling Affect in Humans: A Review.” Journal of Psychiatry and Neuroscience, 1993; 19(5):235-244.
4 Cooney, C, et al, “Methamphetamine Treatment Affects Blood and Liver S-Adenosylmethionine (SAM) in Mice: Correlation with Dopamine Depletion in the Striatum.” Annals of the New York Academy of Sciences, 1998; 844:191-200.
5 Malakar, D, et al, “Protective role of S-adenosyl- methionine agains hydrochloric acid stress in Saccharomyces cerevisiae.” Biochimica et Biophysica Acta (BBA), 2006; 1760(9):1298-1303.
6 Mischoulon, D, et al, “Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence.” The American Journal of Clinical Nutrition, 2002; 76:1158S-1161S.
7 Friedel, HA, et al, “S-adenosyl-L-methionine. A review of its pharmacological properties and therapeutic potential in liver dysfunction and affective disorders in relation to its physiological role in cell metabolism.” Drugs, 1989; 38(3):389-416. |
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