Find a source of Stearidonic acid. You avoid the inherent limitations of the Delta-6-Desaturation of ALA, and it is readily enlogated and desaturated to EPA. It would also act as a competetive inhibitior of the Delta-5-Desature enzyme that converts DGLA to AA.
Sources are:
Black Currant Seed Oil (2-4%)
Echium Oil, a member of the Boraginaceae family (up to 20%)
http://www.nutraingredients.com/new...patent-for
One caveat--because these oils are derived from seeds, they may also have a high omega-6 content.
Michael J James, et al
[i:e5a17cd75d]"Metabolism of stearidonic acid in human subjects: comparison with the metabolism of other n-3 fatty acids"[/i:e5a17cd75d] American Journal of Clinical Nutrition, Vol. 77, No. 5, 1140-1145, May 2003
Virginia M. Ursin
[i:e5a17cd75d]"Modification of Plant Lipids for Human Health: Development of Functional Land-Based Omega-3 Fatty Acids" [/i:e5a17cd75d]J. Nutr. 133:4271-4274, December 2003
Marc E. Surette, et al [i:e5a17cd75d]"Dietary Echium Oil Increases Plasma and Neutrophil Long-Chain (n-3) Fatty Acids and Lowers Serum Triacylglycerols in Hypertriglyceridemic Humans"[/i:e5a17cd75d] J. Nutr. 134:1406-1411, June 2004