NSAIDS and eicosanoid balance?
Last Post 10 Aug 2012 05:16 PM by Sue. 52 Replies.
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Jonathan
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10 Aug 2012 08:15 AM
P.s.,

This is the first I've ever heard of the "ESR." An alternative is going by "feel" and quality of stool. I can't remember where this came from, but 10 or 15 years ago, Dr. Sears gave following guidelines:

Overproduction of 'good' eicosanoids produces a very loose stool or diarrhea Overproduction of 'bad' eicosanoids produces a very dense stool or constipation. Optimal balance of 'good' and 'bad' eicosanoids produces a floating stool. (zone) If you are making too many ‘good’ eicosanoids, cut back your intake of EPA. (zone)
Any increase in grogginess upon waking is indicative of over-production of 'bad' eicosanoids Too many ‘bad’ eicosanoids, increase your intake of EPA and cut back your intake (no matter how limited) of GLA.
cranberrycat
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10 Aug 2012 08:21 AM
I agree, and I am really surprised that I allowed this to go so far, without thinking about it.

Part of the problem is with regard to how doctors handle it... mine was totally fine with me taking an NSAID longterm. And, I could get in the Zone, but it was just way to easy for me to become sidetracked, and was never able to really figure out why that was happening. I am already noticing the difference. I am actually not experiencing the heel pain that I was having for the past 2 years, and the knee pain that is more chronic is really no worse.

I do have an upcoming surgical procedure, though, which will probably sideline me again for a bit, but since Ibuprofen is one of the more mild NSAIDs, I will probably just use that for the short-term.
Cranberrycat

We don't own the earth; we borrow it from our children.


Sue
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10 Aug 2012 05:16 PM
[quote]
Posted By Jonathan on 10 Aug 2012 09:15 AM
P.s.,

This is the first I've ever heard of the "ESR." An alternative is going by "feel" and quality of stool. I can't remember where this came from, but 10 or 15 years ago, Dr. Sears gave following guidelines:

Overproduction of 'good' eicosanoids produces a very loose stool or diarrhea Overproduction of 'bad' eicosanoids produces a very dense stool or constipation. Optimal balance of 'good' and 'bad' eicosanoids produces a floating stool. (zone) If you are making too many ‘good’ eicosanoids, cut back your intake of EPA. (zone)
Any increase in grogginess upon waking is indicative of over-production of 'bad' eicosanoids Too many ‘bad’ eicosanoids, increase your intake of EPA and cut back your intake (no matter how limited) of GLA.
[/quote]

This is info from Dr. Sears' books regarding how to interpret two of items in the ESR, stool density and grogginess upon waking.
Sue Knorr

Lost 100 lbs 18 yrs ago, off BP meds, thanks to the Zone diet and Zone fish oil.

Consultant of Zone Labs
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