Again, scientific studies confirms Dr Sears.
Let's see, 2.5 grams, that's about 4 of Dr. Sears Omega-3 capsules.
And that is also Dr. Sears Recommended amount way back in his "The Omega RX Zone" book.
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Lee Swanson Research Update
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Anti-Inflammatory Potential of Omega-3s Shown in Overweight People
June 28, 2012
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Supplements of omega-3 fatty acids may reduce levels of certain inflammatory markers by 10%, says a new study that claims to be the first to show omega-3 supplementation may alter inflammatory markers in overweight but otherwise healthy people.
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Four months of supplementation with 2.5 grams or 1.25 grams of omega-3s led to decreases in levels of pro-inflammatory cytokine interleukin-6 (IL-6) of 10% and 12%, respectively, compared with a 36% increase in the placebo group.
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Chronic inflammation is brought about by an over-expression or lack of control of the normal protective mechanisms, and it has been linked to a range of conditions linked to heart disease, osteoporosis, cognitive decline and Alzheimer's, type 2 diabetes and arthritis.
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"Our data suggest that omega-3 PUFAs can reduce inflammation in overweight, sedentary middle-aged and older adults, and thus could have broad health benefits," wrote researchers from Ohio State University in Brain, Behavior and Immunity.
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"Although the omega-3 PUFAs cannot take the place of good health behaviors like exercise, individuals who are at risk because of established inflammatory diseases or conditions may profit from their use.
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"These data provide a window into the ways in which the omega-3 PUFAs may impact disease initiation, progression and resolution."
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The Ohio State researchers, led by Professor Jan Kiecolt-Glaser, recruited 138 adults with an average age of 51. Ninety-one percent of the participants were overweight and 47% were obese. They were randomly assigned to receive placebo or 1.25 or 2.5 grams per day of omega-3.
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The daily doses of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were 868.75 mg and 145 mg, respectively, in the low-dose group and 2,085 mg and 348 mg, respectively, in the high-dose group.
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"We chose the 7:1 EPA/DHA balance because of evidence that EPA has relatively stronger anti-inflammatory and antidepressant effects than DHA," explained Kiecolt-Glaser and her co-workers.
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After four months of supplementation, results indicated significant reductions in IL-6 levels, compared with placebo.
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Levels of the cytokine tumor necrosis factor-alpha (TNF-alpha) also decreased by 0.2% and 2.3% in the low- and high-dose groups, respectively. The placebo group's TNF-alpha increased by an average of 12%.
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"This is the first study to show that omega-3 supplementation leads to changes in inflammatory markers in the blood in overweight but otherwise healthy people. In terms of regulating inflammation when people are already healthy, this is an important study, in that it suggests one way to keep them healthy," said Kiecolt-Glaser.
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The researchers also sought to determine whether omega-3 fatty acids could reduce depression symptoms, but participants had relatively few symptoms to begin with so no significant reductions were seen.
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Brain, Behavior and Immunity; Published online ahead of print.
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