These are my notes on asthma.
In my opinion, yes your husband should experiment with higher doses of fish oil.
He should also look at improving hygiene with clean zone soap and facial dips to remove the load of potential triggers.
I hope this helps.
Eicosanoids and asthma.
Asthma is characterized by inflammation and spasms of the bronchial passages.
These spasms restrict the flow of air into and out of your lungs making breathing difficult.
The inflammation which leads to the bronchial constriction is caused primarily by bad eicsoanoids called leukotrines.
Also involved are bad eicosanoids called cytokines (like IL-4, IL-5 and IL-6) which cause an overactive immune response when you body is exposed to triggers like allergens, bacteria and viruses.
Low levels of cyclic AMP (a secondary messenger inside your cells) also seem to be involved in the bronchial constriction of asthma. (Good eicosanoids increase the production of cyclic AMP).
The prescription drug Hydergine also helps relieve asthma increasing levels of cyclic AMP. Corticosteroids work by stopping the production of eicosanoids and leukotrine receptor antagonists help slow down the production of leukotrines.
So increasing levels of good eicosanoids and decreasing levels of bad eicosanoids is essential to relieve the symptoms of asthma both by reducing the levels of leukotrines and cytokines (bad eicosanoids) and increasing the levels of cyclic AMP.
The good eicosanoid PGE1 also helps your blood vessels relax increasing circulation.
This can increase the blood flow to the capillaries of your lungs which would help them extract oxygen more efficiently.
Fish oil can help your body produce more good eicosanoids and reduce the production of the bad eicosanoids like leukotrines and cytokines.
As with most inflammatory diseases the dosage required of fish oil is quite high.
8-16 capsules a day of pharmaceutical grade fish oil is recommended. (2-4 teaspoons)
The dose may need to be higher if symptoms persist.
The dosage can usually be reduced once symptoms disappear.
As an absoloute minimum sufferers of asthma should take 4 health food grade fish oil capsules every day.
Consider taking one 500mg capsule of evening primrose oil every week.
The GLA in evening primrose oil can help in the production of good eicosanoids.
Take vitamin C in 4-6 daily doses (even more often if possible).
Each dose should be 250mg to 1000mg.
In times of particular stress or at the onset of respiratory illness titrate to bowel tolerance.
Vitamin C has many effects. Probably most important it can act as a natural antihistamine reducing allergic response.
Take 500iu to 2000iu of vitamin E daily. Vitamin E could help by inhibiting your body’s production of leukotrines.
The most common cause of excess inflammation is a poor diet producing excess insulin and cortisol which leads to the excess production of bad eicosanoids which cause inflammation.
Follow the basic diet outlined in any of my books to help your body produce more good eicosanoids and less bad eicosanoids.
Also look for foods and additives in foods that can trigger asthma attacks.
Common triggers are sulfites, tartrazine (yellow dye #5), sodium benzoate, natural salicylates, high salt intake could be linked, caffiene, chlorinated tap water and natural salicylates. Also consider the usual allergy suspects milk, wheat products and soy products.
Avoid saturated fats.
A high intake of saturated fats (found in animal fats) has been linked to asthma.
Good fats (almonds, avacados, fish oil) reduce the risk.
So choose low fat sources of protein (turkey breast, chicken breast, fish, tofu, whey protein isolate).
Asthma attacks are also linked to pollution and other environmental triggers including smoke, animal fur, chemicals, pollens and dust mites.
Since contact from the fingernails to the mucus membranes of the eyes and nose is a primary method of tranmitting allergens, bacteria and viruses effective cleaning of the fingernails (clean zone soap from www.advancedhygieneproducts.com ) should help reduce this form of self innoculation.
Don’t pick your nose. Picking your nose can cause damage which leads to an immune response and a subsequent asthma attack.
Facial dips can also help wash away the triggers of an asthma attack reducing the chance of an attack and the chance of secondary infections, colds and viruses which can increase the severity of the condition.
Details of perfoming facial dips are in both my books available for free download from www.geocities.com/glorioushealth
Consider adding a teaspoon of sea minerals to the facial dip solution to provide isotonic magnesium. (Although it may not have much effect isotonic magnesium added to other inhaled formulas helped relieve the symptoms of asthma in one study. And sea minerals are cheap).
Smoking reduces lung capacity which can make it more difficult to breathe when you have an attack.
Cigarette smoke could also bring on an attack.
Cigarette smoke also retards the healthy functiong of cillia (hairs in your nose) which help remove allergens etc from your nasal passageways.
REDUCE STRESS (EMOTIONAL HEALTH)
Reducing stress helps relieve the symptoms of asthma almost certainly by reducing the levels of cortisol the stress hormone.
Excess cortisol leads to the overproduction of bad eicosanoids.
Learn a relaxation response to stressful situations.
Learn methods for relieving negative emotions (EFT works well).
Exercise also helps lower your body’s levels of cortisol.
Exercise can improve lung capacity making breathing easier.
Asthmatics should be particulary cautious to build up to an exercise program slowly and never over exercise which can lead to an attack.
Try to improve the quality and quantity of sleep which is often compromised in asthma sufferers.
Higher levels of naturally produced melatonin have been linked to asthma attacks at night. There are no studies that show supplemental melatonin is linked to increased asthma attacks but it would be wise to show caution with supplemental melatonin to improve sleep if you suffer from asthma attacks at night.
Keep in mind that melatonin acts as an antioxidant in particular preventing the breakdown of fats. Fats like linoleic acid, GLA and DGLA can be made into both good or bad eicosanoids. If you are producing excess insulin and/or cortisol chances are that many of these fats will be turned into bad eicosanoids.
If your insulin and cortisol are under control you’ll probably turn these fats into more good eicosanoids than bad.
Lyprinol comes from New Zealand green lipped mussel powder.
It contains omega 3 fatty acids like fish oil but is particularly high in eicosatetraenoic acids (ETAs).
Very preliminary studies suggest that these ETAs may be particularly effective in reducing levels of inflammation particularly in cases of asthma and rheumatoid arthritis.
One study claims that lyprinol is 250 times more potent than salmon oil.
The research is still very thin but seems promising.
The herb boswellia seratta can slow down your body’s production of leukotrines by inhibiting the 5-lipoxygenase enzyme involved in its production.
Clinical trials of boswellia showed promise in treating bronchial asthma.
Gingko biloba is a herb which could block the action of platelet-activating factor (PAF) which is involved in producing the symptoms of asthma.
Gingko biloba can also help increase circulation.
Lycopene found in tomatoes and tomato paste can help reduce asthma caused by exercise. Tomatoes are an excellent source of low glycemic carbohydrates.
If you supplement with lycopene 30mg a day is suggested.
The trace mineral selenium could help protect against the free radical damage of asthma and may help reduce symptoms.
Three brazil nuts a day or 200mcg of selenium should be enough.
One study showed combining apples and selenium supplementation helped reduce the symptoms of asthma.
Apples are a good source of carbohydrates.
Quercetin is a flavinoid found in citrus fruits which inhibits an enzme called lipoxygenase. Lipoxygenase contributes to problems with asthma.
So increase your consumption of citrus fruits as a source of carbohydrates in your diet.
The mineral magnesium may help improve lung function and decrease bronchial reactivity. This could help prevent spasms of the bronchial passages.
300mg to 400mg of magnesium a day is recommended. If you add sea minerals in your drinking water you’ll achieve this dose quite easily.
Loss of bone density has been associated with asthma so it’s also worth supplementing with 1000mg or so daily of calcium.
BETAINE HCL AND PANCREATIC ENZYMES
One study showed that 80% of children with asthma had hypochlorydia (low stomach acid). Supplementation with betaine HCL and pancreatic enzymes can help restore normal digestion in cases of hypochlorydia.
Taking an acidophilus/bifidus capsule daily between meals may also help in the proper digestion of nutrients. This is highly recommended if you’ve taken a course of antibiotics which can destroy your intestinal flora.
One study found that coenzyme Q10 levels were significantly lower in the plasma and blood of asthma sufferers. If you choose to take coenzyme Q10 100mg a day is suggested.
An example of how EFT (a method for relieving negative emotions) can help with asthma attacks. This whole method seems bizaare but the rapid positive results are commonplace.
I hope you find at least some of this information useful.