Why doesn’t exercise and diet reduce heart disease for diabetics?

That’s a good question after the June 24 issue of the New England Journal of Medicine reported on the failure of long-term diet and exercise to reduce heart disease in diabetics1. It had been known from earlier and shorter studies that diet and exercise in diabetics appeared to generate a decreased risk of cardiovascular disease…. Read more »

Harvard explains why people regain weight with the Atkins diet

A study from Harvard Medical School explains that even though people can lose weight on a ketogenic diet, all lost weight usually rapidly returns. Ketogenic diets have been recommended for decades for rapid weight loss. The most famous is the Atkins diet. Ketogenic diets are based on high-protein and very low-carbohydrate intake. For the past… Read more »

“Biggest Loser” or best Zoner?

A few weeks ago I spoke at the American Society of Bariatric Physicians. Later in the day I heard an interesting lecture from the lead dietician for the TV series “The Biggest Loser”. In this lecture, she disclosed all the keys for successful weight loss in the individuals on the show. The first was incredibly… Read more »

Changing gene expression

I have often stated that the real power of the Zone Diet is to change gene expression, especially the expression of anti-inflammatory genes. What I never realized is how rapid gene expression could occur.

Eat Less, Get Hungry

Telling an obese person simply to eat less rarely succeeds. Is it because they are weak-willed individuals or is there something more complex going on?

Zone diet validation studies

Every now and then it’s worth going back over the published literature to see how the Zone diet stacks up in various areas of nutritional research.

Where does fat go?

The fastest and most popular (although costly) way to lose fat is to simply suck it out of the body.

Fish oil and fat loss

One of the best ways to reduce cellular inflammation in the fat cells is by increasing your intake of omega-3 fatty acids.

Omega-3 fatty acids and blood pressure

It was recognized many years ago that fish oil has a dose-dependent effect on lowering blood pressure. So how does it do it? There are a lot of different ways.

What is the Mediterranean diet?

Today we continually hear about the health benefits of following a Mediterranean diet. For example, a recent analysis of more than 50 published studies indicated that a Mediterranean diet would lead to a 30-percent reduction in metabolic syndrome (1). Since metabolic syndrome can be considered pre-diabetes, the public health implications are enormous. However, are we… Read more »