Lights off for weight loss

I have often said that weight loss is a lot more complicated than simply “eating less and exercising more”. New research indicates how much more complicated weight gain is due to circadian rhythms. Our brain and virtually all of our cells are programmed to run on a 24-hour cycle to help us optimize future events… Read more »

Try the team approach to nutrition

One of the problems with nutrition is that it is too complex for simple thinking. Unlike drugs, which are designed to inhibit a particular target enzyme, nutrients often work in combinations like a team operating at the genetic level. When you try to apply drug-like thinking (i.e. one compound has to do all the work)… Read more »

Increased satiety: The real secret to weight loss

Satiety is defined as lack of hunger. If you aren’t hungry, then cutting back calories is easy. Unfortunately, Americans seem to be hungrier than ever. This is not caused by a lack of willpower but due to hormonal imbalances in the hypothalamus that tell the brain to either seek more food or spend time on… Read more »

The secret of blueberries: It’s the dephinidins

We continually hear about the benefits of fruits and vegetables for better health. There are a number of them. One is obviously their lower glycemic load that reduces insulin secretion. Another is their polyphenol content that gives fruits and vegetables their colors. Although virtually no research was conducted on polyphenols before 1995, since that time… Read more »

Want to lose Weight? Eat like our Paleolithic ancestors

A recent article appeared in the British Journal of Nutrition that gives an updated estimate of what diet (i.e. Paleolithic) our ancestors may have eaten during the time from their first appearance in Africa some 200,000 years ago until they started leaving Africa 100,000 years later (1). This is important because this type of diet… Read more »

Aspirin…not just for heart disease

As I pointed in my first book, “The Zone,” more than 15 years ago, aspirin remains a wonder drug because of its ability to reduce inflammation (1). The medical community now uses aspirin for the prevention of strokes and heart attacks, but a recent study may extend its anti-inflammatory benefits to cancer survivors. A study… Read more »

Does eating fat make you fat?

The 1990s brought with it an era of people fearing fat. After all, “if no fat touches my lips, then no fat reaches my hips”. Harvard took charge of this debate and declared war against fat, especially saturated fat. Manufacturers created everything from fat-free yogurt to cookies. Overall, fat intake did decrease nationwide during this… Read more »

Eat your breakfast

You’ve probably heard it a billion times. “Don’t skip breakfast!” But most Americans, adults and children, are not heeding this advice. There are a bunch of reasons why you should eat breakfast within one hour of waking. And it’s even better if the meal is Zone balanced – the correct amount of lean protein, low-glycemic… Read more »

The Mood-lifting properties of B-vitamins

In a previous blog we addressed the impact of omega-3 fatty acids and their mood-lifting properties, and now it looks like we can add certain B-vitamins to the list. A recent publication in the American Journal of Clinical Nutrition looked at whether dietary intakes of vitamin B-6, B-12 and folate had an association with depressive… Read more »

More bad news on Toxic Fat with a glimmer of hope

Last month, I discussed disturbing new data on the impact of omega-6 fatty acids on genetic expression (Cardiovascular Psychiatry and Neurology (2009;2009:867041). At the recent International Fatty Acid Conference in the Netherlands I had the opportunity to talk with Joe Hibbeln, the lead author, of that study at length. During the conference, his group presented… Read more »